adoptive transfers การใช้

• The body is thus prepared for restoration of immune function by adoptive transfer of new lymphocytes.
• Another approach is adoptive transfer of haploidentical ?? T cells or NK cells from a healthy donor.
• For example, adoptive transfer is used to study the effects of lymphocytes in the absence of other lymphoid cells.
• Research on adoptive transfer in melanoma patients laid the groundwork for companies focusing on adoptive transfer research in other types of cancer.
• Research on adoptive transfer in melanoma patients laid the groundwork for companies focusing on adoptive transfer research in other types of cancer.
• Cancer therapy targeted at tumor antigens can involve the direct use of these antigens in vaccines, but also the adoptive transfer of T cells that recognize these antigens.
• The adoptive transfer of tumor-specific effector T cells knocked out or knocked down for CISH resulted in a significant increase in functional avidity and long-term tumor immunity.
• The second treatment, adoptive transfer of genetically altered autologous lymphocytes, depends on delivering genes that encode so called T cell receptors ( TCRs ), into patient's lymphocytes.
• Adoptive transfer of T cells expressing chimeric antigen receptors is a promising anti-cancer therapeutic as CAR-modified T cells can be engineered to target virtually any tumor associated antigen.
• In a study run at the University de la Sante, the adoptive transfer of cloned T cells in  in vitro immunization caused increased frequencies of cancer fighting T cells in 18 out of 35 melanoma patients.
• Adoptive transfer involves either collecting from patients intratumoral or blood T cells, stimulate them " in vitro " against antigens present in the tumors and reinfuse them in large number into the patients, or using gene-modified T cells that recognize a tumor antigen.
• CD4 + T cells polarized with IL-23 and IL-6 are pathogenic upon adoptive transfer in type 1 diabetes while cells polarized with TGF-beta and IL-6 are not pathogenic ., The intracellular aryl hydrocarbon receptor ( AhR ), which is activated by certain aromatic compounds, is specifically expressed in Treg17 cells.